Evaluation of Hepatoprotective, Analgesic and Antipyretic Activity of Aqueous Extracts of Boerhaavia Diffusa and Anisochlilus Carnosus

نویسنده

  • P. Rami Reddy
چکیده

An aqueous extracts of stem and leaves of Boerhaavia Diffusa (Aq.EBD) and leaves of Anisochilus Carnosus (Aq.EAC) was studied for hepatoprotective, analgesic and antipyretic activity. Hepatotoxicity was introduced in Albino rats of either sex by intraperitoneal injection of CCl4 (in olive oil). Tail immersion method and Hot plate method in mice were studied for analgesic activity, Yeast induced pyrexia method in rats was followed to evaluate antipyretic activity. Aq.EBD and Aq.EAC were administered to the experimental animals at the dose levels 150mg and 300mg/kg body weight, 200mg and 400mg/kg body weight of Aq.EBD and Aq.EAC respectively. The hepatoprotective effects of the extracts were evaluated by the assay of liver function biochemical parameters like Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Tranaminase (SGPT), Serum Alkaline Phosphatase (SALP), Total and Direct Serum Bilirubin. It was concluded that, the Aq.EBD and Aq.EAC possess hepatoprotective activity against CCl4 induced hepatotoxicity in rats, in both analgesic methods the extracts has shown significant activity and the dose was also shown significant results for antipyretic activity.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of Hepatoprotective, Analgesic and Antipyretic Activity of Aqueous Extracts of Boerhaavia Diffusa and Anisochlilus Carnosus

An aqueous extracts of stem and leaves of Boerhaavia Diffusa (Aq.EBD) and leaves of Anisochilus Carnosus (Aq.EAC) was studied for hepatoprotective, analgesic and antipyretic activity. Hepatotoxicity was introduced in Albino rats of either sex by intraperitoneal injection of CCl4 (in olive oil). Tail immersion method and Hot plate method in mice were studied for analgesic activity, Yeast induced...

متن کامل

Evaluation of Boerhaavia Diffusa for Hepatoprotective Activity in Experimental Wistar Rats

Boerhaavia diffusa (Nyctaginaceae) is conventionally used in Indian Ayurvedic system to treat liver diseases. The present study was undertaken to investigate the protective role of ethanol extract of B. diffusa on hepatic antioxidant status and the levels of diagnostic markers in isoproterenol induced hepatitis in rats. The Prior oral administration of B. diffusa extract [150 mg/kg bodyweight/d...

متن کامل

Pharmacognostical Evaluation and Qualitative Analysis of Boerhaavia Diffusa L. Roots

Boerhaavia diffusa L. (Family: Nyctaginaceae) is an herbaceous plant, spreading vine widely distributed in the tropical and subtropical regions in the world. The plants are a rich source of vitamins, minerals, protein and carbohydrate. In Punjab region, the drug is useful for the eye disease and in Bombay used for dropsical swellings. The leaves juice is used in jaundice and the root is general...

متن کامل

Evaluation of Antipyretic Activity of Pedalium murex Against Brewer’s Yeast-Induced Pyrexia in Rats

The aqueous and ethanolic extracts of Pedalium murex (Pedaliaceae) was investigated for antipyretic activity in rats using Brewer’s yeast-induced pyrexia models. Brewer’s yeast (15%) was used to induce pyrexia in rats. Both the extract (200 and 400 mg/kg body weight p.o produced a significant (p

متن کامل

Studies on Anti-inflammatory, Analgesic and Antipyretic Properties of Methanol Extract of Caesalpinia bonducella leaves in Experimental Animal Models

The methanol extract of Caesalpinia bonducella leaves were investigated for anti-inflammatory, analgesic and antipyretic activity at the doses of 50, 100 and 200 mg/kg, body weight. The experimental paradigms used were carrageenan, dextran, histamine induced pedal edema and cotton pellet induced granuloma for anti-inflammatory activity, while hot plate and acetic acid induced writhing methods w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013